Adelphi Group

Ask the Expert: XYZ Distributor

15/12/25

IMG 8891

Adelphi Manufacturing’s ISO-certified, award-winning design team has developed an advanced solution for hygienic and accurate filling. By adapting the XYZ Distributor, this system can now securely hold pre-sterilised nested syringes in place for precise, contamination-free dosing - ideal for pharmaceutical, biotech, and clinical trial production environments.

When paired with the Accuramatic Peristaltic Pump, the XYZ Distributor forms a semi-automatic peristaltic syringe filling machine. This setup provides fast, sterile, and repeatable filling for nested syringes, vials, and small bottles, making it an excellent choice for GMP-compliant sterile manufacturing.

Why Choose the XYZ Syringe Filling Solution?

 

1️. Sterile, Closed-System Design

Your product only comes into contact with the inside of a single uninterrupted length of platinum-cured silicone tubing, which can withstand repeated sterilisation.

  • Eliminates cross-contamination risks between batches.
  • Maintains a completely closed sterile pathway, critical for injectable and biologic products.

2️. Optimised for Cleanroom Use

For enhanced sterility, many customers operate the XYZ Distributor within:

  • Laminar flow cabinets
  • Glove boxes or isolator systems

This ensures aseptic conditions suitable for sterile fills.

3️. Optional Bacteriological Inline Filtration

The system supports bacteriological inline filtration at the pump outlet, ensuring the highest level of microbiological safety by filtering product immediately prior to dispensing.

4️. Rapid Product Changeovers

The disposable silicone tubing can be removed and replaced in seconds, making it easy to switch between products without lengthy cleaning cycles. This reduces downtime and boosts operational flexibility - ideal for small-batch or multi-product facilities.

5️. Precision and Reliability

The Accuramatic Peristaltic Pump offers filling accuracy of ±0.25%, reducing costly overfill and ensuring repeatable quality with every batch. Combined with the XYZ Distributor’s secure syringe positioning, this system supports precise, compliant syringe filling.

How the System Works

1️. Place pre-sterilised nested syringes into the XYZ Distributor.
2️. The Accuramatic Peristaltic Pump fills via sterile platinum-cured tubing.
3️. Optional inline filtration ensures sterility at the point of fill.
4️. Replace tubing for rapid, contamination-free changeovers.

FAQ: Nested Syringe Filling

  • What is nested syringe filling?

    Nested syringe filling involves accurately dosing pre-sterilised syringes that are supplied in trays (‘nests’). This reduces manual handling, speeds up production, and ensures compliance with aseptic requirements.

  • How does peristaltic filling reduce contamination?

    A peristaltic pump moves product through sterile tubing, eliminating contact with pump components and preventing cross-contamination.

  • Why use platinum-cured silicone tubing?

    Platinum-cured tubing is highly durable, biocompatible, and can withstand repeated sterilisation - essential for sterile manufacturing environments.